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    Grand building, but judging from the foot traffic outside Union Station this was not a big day for travel by train. Photo taken 2008.

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  • San Antonio's River Walk is a nice spot -- and...

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    San Antonio's River Walk is a nice spot -- and the $29,305.47 you'll need to live there also hits the spot.

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    The beautiful Seattle, Wash., skyline from atop Queen Anne Hill at the Kerry Park overlook.

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    Boston skyline from waterfront.

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    historic French Quarter in New Orleans, Louisiana - USA

  • Minneapolis comes in as the ninth-best U.S. destination to travel...

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    Minneapolis comes in as the ninth-best U.S. destination to travel with pets.

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    Cherry trees blossom near the Washington Monument on the National Mall in Washington on April 11, 2015. The cherry blossoms were a gift from Japan.

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  • Wandering through hilltop neighborhoods like Troy Hill or Polish Hill...

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    Wandering through hilltop neighborhoods like Troy Hill or Polish Hill offers the chance to check out cool indie coffee shops and record and book stores, as well as take in the views of the rivers and city below.

  • Dusk, Broad Street, Philadelphia, PA.

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    Dusk, Broad Street, Philadelphia, PA.

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Chicago is second to none in the eyes of Conde Nast Traveler readers, who ranked the Midwest city No. 1 in its 2017 list of best U.S. large cities (greater metro areas with populations 1 million-plus). Click through to see which locales made the cut in this year’s Readers’ Choice Awards survey, and get the full story here.