Seven-time champion Rafael Nadal methodically wore down Denis Shapovalov 6-4, 6-1 Thursday to reach the Italian Open's last eight and gain revenge over the Canadian teenager.
Four-time Rome winner Novak Djokovic reached his first quarterfinal of the year with a 6-1, 7-5 victory over Alberto Ramos-Vinolas.
Djokovic next faces Kei Nishikori, who rolled past Philipp Kohlschreiber 6-1, 6-2.
The 19-year-old Shapovalov stunned Nadal in the third round in Montreal last year to deny the Spanish player a chance to regain the No. 1 spot.
Nadal is also attempting to win the top spot back this week. He'll replace Roger Federer if he wins an eighth Rome title.