Gaining at least a point on Tuesday at Honduras is critical for the United States' chances to qualify for an eighth straight World Cup.
Mexico clinched one of the three berths from North and Central America and the Caribbean on Friday night, and Costa Rica is close to securing another.
After its second home loss in the hexagonal, the U.S. is clinging to third place, ahead of Honduras on goal difference. A draw or win against the Catrachos would leave the U.S. in position to secure a berth with wins against Panama on Oct. 6 at Orlando, Florida, and at last-place Trinidad and Tobago four days later.
"We'll respond in a big way," U.S. captain Michael Bradley...