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The Latest: It's all about guts at Super Bowl 50

The latest developments in Super Bowl commercials before, during and after the Big Game:

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9:50 p.m.

Maybe it really does take guts to win the Super Bowl — at least if you're an advertiser hoping to stand out in the scrum.

First there was an ad about "opioid-induced constipation." Then another followed for a drug that treats abdominal pain and diarrhea.

The first ad featured a man eyeing prunes in a store window and envying another man who went in a public bathroom with ease. The latter ad was more cerebral; in it, a cartoon pile of pink intestines travels to a big football game, only to face a sudden urge to, well, go. With a drug...

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