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Andy Reid

Smith, Chiefs run over Lions 45-10 at Wembley Stadium

When Alex Smith had no options left, he ran. And he ran far.

The Kansas City quarterback carried the ball five times and gained 78 yards, including a career-high 49-yard scramble in the second quarter that set up his 12-yard touchdown run.

With a comfortable lead in hand, Smith settled into his usual role, throwing for 145 yards and a pair of touchdowns to lead the Chiefs to a 45-10 victory over the Detroit Lions at Wembley Stadium in the last of three regular-season NFL games in London.

"We got a lot of guys with a lot of different strengths," Smith said. "We can present a lot to a defense. It's hard for them to defend."