The romantic comedy also stars Julia Louis-Dreyfus and is directed by Nicole Holofcener.
The film is premiering at the Toronto Film Festival and, while it doesn't look to be Oscar bait, could play with the Golden Globe crowd. The trailer highlights suggest that the feature will show a softer side of Gandolfini, who is most famous for playing hardened crime boss Tony Soprano for HBO's "The Sopranos."
The film opens in theaters on Sept. 20.
© 2013 Variety Media, LLC, a subsidiary of Penske Business Media; Distributed by Tribune Content Agency, LLC