The gated one-third-acre property includes a 1922 Mediterranean-style house and a swimming pool. The 4,600-square-foot home has four bedrooms and 41/2 bathrooms.
"Arthur," released in April, as well as "Get Him to the Greek" (2010) and "Forgetting Sarah Marshall" (2008).
They own a pied-a-terre in New York and recently bought a Sunset Strip-area compound for $6.5 million.
Public records show the couple bought the Los Feliz house in 2009 for $3.25 million.
Ernnie Carswell and Christopher Pickett of Teles Property, Beverly Hills, were the listing agents. David Findley of Partners Trust, Beverly Hills, represented the buyer.