Lizzy Caplan | Showtime's 'Masters of Sex'
Her role: Set in the 1950s Eisenhower era, the drama follows Caplan as she portrays arousal analyst Virginia Johnson. Twice-divorced and a single mom, Caplan's character researches alongside the brilliant and curious Dr. William Masters, played by actor Michael Sheen. The pair are ultimately credited as the pioneers of human sexuality, unleashing the sexual revolution of the 1960s.
Where we've seen her before: Caplan played outcast and friend to Lindsay Lohan in the film "Mean Girls." On television, she's known for her small but recurring roles on "New Girl" and "True Blood." (Craig Blankenhorn / Showtime /March 21, 2012)
Linda Cardellini will soon be joining the cast of Fox's "New Girl" in a recurring role as Zooey Deschanel's character's sister.