Giselle Esteban

Hayward police said they arrested Giselle Esteban, the former high school friend of Michelle Le, at her home in Union City Wednesday morning. Esteban is being held at the Hayward jail. (Hayward Police Department / September 7, 2011)

HAYWARD,Calif. -- Police made an arrest Wednesday in the case of a missing nursing student from San Diego, officials announced.

Hayward police said they arrested Giselle Esteban, the former high school friend of Michelle Le, at her home in Union City Wednesday morning. Esteban is being held at the Hayward jail.

"No one should have to deal with a loved one missing,"said Le's brother Michael at a press conference Wednesday, "We just want her home as soon as possible."

In June, Esteban told a San Francisco television station in an interview that she "openly hates" Le, claiming the missing woman stole her boyfriend. But Esteban also told the station she had nothing to do with Le's disappearance.

"There's been nothing in our investigation that supports anybody else's involvement in Michelle's demise other than Esteban," said Hayward Police Lt. Roger Keener.

Esteban's Rancho Penasquitos home was empty Wednesday.  Neighbors said they hadn't seen the family often since the case began.

Le, who grew up in Rancho Penasquitos and Mira Mesa, disappeared May 27 from Kaiser Permanente Hayward Medical Center in Hayward. She was studying to become a nurse at Samuel Merritt University in San Mateo.

Le, 26, told a colleague she was going to her car, which was parked in the hospital lot. She never returned, and police found her car parked a few blocks away.

Hayward police said Le was the victim of homicide, based on blood evidence found in a parking lot, surveillance video, and statements from witnesses.

Le's body has never been found, and family members in San Diego have insisted she is alive. They have offered a $100,000 reward for information leading to her safe return.

Hayward Police said its investigation would not be completed until Le's body is found.