Juvonte Reddic had 16 points and nine rebounds for the Rams (24-6, 12-3), who moved into a first-place tie atop the Atlantic 10 standings when Saint Louis lost to Xavier in overtime later in the night.
Cedrick Lindsay scored 22 points for Richmond (17-13, 7-8), which beat VCU in overtime in January.
The Spiders were poised to knock off their crosstown rival again, with a Terry Allen 3-pointer tying the game at 79 with 3:13 remaining. But a Graham layup ignited a game-sealing 11-0 run.
Maurice Kemp had 29 points and nine rebounds as host East Carolina edged Tulane. Miguel Paul added 13 points and 11 assists for the Pirates (17-11, 8-7 Conference USA). Tulane’s Josh Davis had 23 points and 16 rebounds.
Patriot League quarterfinals:
Mike Muscala registered 15 points and 13 rebounds to lead the top-seeded Bucknell Bison to a 58-42 home win over No. 8-seeded Navy in Lewisburg, Pa.
Tilman Dunbar paced Navy (8-23) with nine points.
Bucknell will stay at home for a semifinal against No. 4 Army, which ousted No. 5 American 65-44 in West Point, N.Y., as Ella Ellis netted 16 points.
No. 7 Holy Cross, coached by Kecoughtan High graduate Milan Brown, saw its season end at 12-18 with a 77-54 loss at No. 2 Lafayette in Easton, Pa.
Seth Hinrichs scored 20 for the Leopards, who were 14-of-26 from 3-point range, and Tony Johnson added 19 points, seven rebounds and five assists.
CAA regular season:
The Tribe led most of the way after overcoming a nine-point deficit with three consecutive 3-pointers to tie the game at 29. ...
Elena Delle Donne scored 24 points, Danielle Parker reached 1,000 career rebounds and No. 16 Delaware scored the first 16 points to defeat visiting Georgia State 86-58.
Parker, playing in her school-record 138th game, had 12 rebounds, and Lauren Carra scored 15 points for the Blue Hens (26-3, 17-0 Colonial Athletic Association), who set a school record with their 22nd consecutive victory, surpassing a mark set last season. ...
Norfolk's Toia Giggetts scored 19 points as James Madison (21-9, 15-3) clinched the CAA’s No. 2 seed, winning 62-53 at Drexel to relegate the Dragons to No. 3.
Giggetts, a former Lake Taylor High star, was 7-for-8 from the field and 5-for-7 on free throws. Kirby Burkholder added 17 points and a game-high 11 rebounds for her ninth double-double of the season.
Hollie Mershon scored 27 for Drexel (20-9, 13-5).
Wednesday's results set up the CAA tournament pairings for The Showplace Arena in Upper Marlboro, Md.
The March 14 game will pit No. 9 UNC Wilmington against No. 8 George Mason.
The March 15 quarterfinals will match the first game's winner against Delaware, No. 5 Hofstra against No. 4 Northeastern, JMU against No. 7 Towson and No. 6 W&M against Drexel.
Big South first round:
Radford converted 25 UNC Asheville turnovers into 25 points to win 56-39 in the Big South tournament's opening round in Conway, S.C.
Radford's Diani Mason tied her season high with 14 points as the Highlanders (15-13) advanced to Friday's quarterfinal against Presbyterian.