Grubbs has been bothered by a toe injury that has shelved him for the entire week of practices, but both he and coach John Harbaugh maintained some hope that he would be available.
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The team ruled out cornerbacks Chris Carr (left hamstring) and Jimmy Smith (high left ankle sprain). Smith's status wasn't a surprise as Harbaugh had said on Monday that Smith would likely miss a few weeks.
The decision to keep Carr from playing ends his streak of playing in all 102 games of his seven-year career. Carr declined to discuss his injury on Friday, but on Thursday, he said he would be prudent about testing his hamstring.
Wide receiver Lee Evans (left ankle) fully participated in practice for the second straight day and is probable. Also probable is fullback Vonta Leach (foot), who was added to the injury report on Friday.
For the Titans, starting strong safety Chris Hope (shoulder) is doubtful. He has not practiced this week.
Starting defensive end William Hayes (shoulder) is questionable. He did not practice Thursday and Friday after being limited Wednesday.
Listed as probable are starting defensive end Jason Jones, backup defensive end Derrick Morgan (knee) and and backup running back Javon Ringer (back). Starting wide receiver Nate Washington (non-injury related) was removed from the injury report.