CINCINNATI Andrew McCutchen drove a 2-2 pitch over the center field wall in the ninth inning on Saturday night to resurrect a game that had turned sour for the Pittsburgh Pirates. Then he did it again in the 11th to lead the Pirates to a 6-5 win against the Cincinnati Reds.

The first homer tied the game 5-5 after starter Charlie Morton gave up two crippling home runs in the sixth inning to erase an early 4-0 lead; the second gave the Pirates the win at Great American Ball Park.

The home runs were his 16th and 17th of the season. The first was off reliever Jonathan Broxton, the second off J.J. Hoover.

The Reds threatened in the 10th inning when Ernesto Frieri walked Ramon Santiago and Todd Frazier to open the inning.

Jay Bruce nearly drove in the winning run with a single to right field off Justin Wilson, but Santiago was cut down at home plate by Gregory Polanco's strong throw to catcher Russell Martin.

Wilson then proceeded to strikeout Ryan Ludwick and Brayan Pena to get out of a bases loaded jam.

The win gives the Pirates a 49-45 record.

The Pirates had manufactured runs in the first, third, and a pair in the fourth to carry a 4-0 lead in what was shaping up to be a dominating start by Morton.

But Morton gave up a two-run homer to pinch hitter Chris Heisey, followed by a three-run, 433-foot blast by Todd Frazier to give the Reds a 5-4 lead.

Morton had history on his side at Great American Ball Park, carrying into Saturday a 3-0 record with a 1.30 ERA in his last four starts at the stadium, dating back to 2011.

He even threw back-to-back, complete game shutouts at Great American on April 15, 2011, and May 18, 2011.

He was clipping along through five scoreless innings, aided by his wicked curveball.

But the sixth inning could not have gone much worse.

Morton walked Zack Cozart to open the sixth, and it cost him quickly.

Heisey came to the plate to pinch-hit for starting pitcher Mike Leake and drove a fastball over the left field wall to cut the Pirates lead to 4-2.

Billy Hamilton, who had struck out in his first two at-bats, then singled and stole second. Next, Morton walked Santiago and suddenly the go-ahead run was at the plate with no outs, prompting a conference with pitching coach Ray Searage.

Morton worked the count full to Frazier, then threw him a fastball.

Frazier clubbed it so convincingly, that McCutchen could do little but turn, take a handful of steps, then stop and watch it go.

Its estimated distance was 433 feet, but the speed of its travel was far more impressive.