Moreno, who accounted for 1,586 total yards and 13 touchdowns as the Denver Broncos starter last season, has been battling a medical issue according to a source.
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The source wouldn't go into specifics about the injury, but said Moreno has been hindered by it for a couple of weeks and needs time off to recovery.
That explains why he's sparingly involved during 7-on-7, and team drills during last week's OTA session, and this week's minicamp practices.
Every tailback but Moreno participated in Thursday's scrimmage, which concluded the team's offseason work.
The Dolphins signed Moreno to one-year, $3 million deal this offseason with the hopes his skill set and versatility would allow him to become Miami's starting tailback. But Moreno has spent most of the offseason working behind Lamar Miller, the incumbent starter, and Daniel Thomas, last year's third down back.
Mike Gillislee and Damien Williams have even gotten reps with Miami's first and second team units.
Moreno, a former University of Georgia standout who is entering his sixth season in the NFL, has roughly six weeks to get healthy, and improve his conditioning before the Dolphins open training camp in late July.
"Knowshon's had a good camp. He brings a lot of energy into the building every single day. He's very good in the meeting rooms," coach Joe Philbin said of Moreno, whom he previously admitted could be in better shape physically. "He's picked up the system well and he's competed hard on the practice field."