Murray eclipsed the old single-game mark of 237, set by Emmitt Smith on a rainy October 31, 1993 in Philadelphia. He also set a new rookie record for yards on the ground in one contest, snapping Tony Dorsett's previously-held record of 206 yards, accomplished on December 4, 1977 -- also in Philly.
It took the pressure off Tony Romo, who threw for 166 yards and two touchdowns on just 14-of-24 completions for the Cowboys (3-3), whose season-high in points helped snap a two-game skid.
Subbing for injured starter Sam Bradford, A.J. Feeley finished 20-of-33 for 196 yards and an interception for the Rams (0-6), who have dropped nine of their last 10 dating back to last December.
Steven Jackson posted 70 yards -- including his team's lone score -- on 18 carries. Brandon Lloyd clocked in with 74 yards on six catches in defeat.