Two lanes — one in each direction — are now open to public traffic, though construction continues at the bridge, officials said.
The $6 million project to replace the bridge, which crosses over railroad tracks owned by the CSX Corp., was jointly funded by CSX and the city, and first closed the bridge in August 2011.
The city had announced a goal of completing the work before the upcoming Star-Spangled Sailabration, set to begin June 13, and other War of 1812 bicentennial events this summer.
The reopening will also allow the Charm City Circulator's new Banner Route to operate between the Inner Harbor and Fort McHenry, officials said. That route is scheduled to start Monday.