UNDERRATED: '50/50'

Can a movie about a 27-year-old's cancer diagnosis be a feel-good picture? As improbable as it sounds, that's what happened with this comedy, which deserves greater notice this fall for not backing away from the harshness of its plot while side-stepping maudlin sentimentality. The chemistry between Joseph Gordon-Levitt and <a class="taxInlineTagLink" id="PECLB005411" title="Seth Rogen" href="/topic/entertainment/movies/seth-rogen-PECLB005411.topic">Seth Rogen</a> is part of it, but so are terrific turns from <a class="taxInlineTagLink" id="PECLB002494" title="Anjelica Huston" href="/topic/entertainment/anjelica-huston-PECLB002494.topic">Anjelica Huston</a>, <a class="taxInlineTagLink" id="PECLB000005048" title="Anna Kendrick" href="/topic/entertainment/movies/anna-kendrick-PECLB000005048.topic">Anna Kendrick</a> and the former "Max Headroom," Matt Frewer.

( Summit Entertainment )

Can a movie about a 27-year-old's cancer diagnosis be a feel-good picture? As improbable as it sounds, that's what happened with this comedy, which deserves greater notice this fall for not backing away from the harshness of its plot while side-stepping maudlin sentimentality. The chemistry between Joseph Gordon-Levitt and Seth Rogen is part of it, but so are terrific turns from Anjelica Huston, Anna Kendrick and the former "Max Headroom," Matt Frewer.

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