The event: The bombing of the Murrah Federal Building in Oklahoma City on April 20, 1995.
The third season of "Melrose Place" was supposed to end with a deranged Kimberly (Marcia Cross) blowing up the apartment complex. Following the Oklahoma City bombing, however, FOX re-edited the finale to show Kimberly pressing the detonator as the screen went black. The explosion and its aftermath were saved until the fourth season premiered that fall.
-- Rick Porter, Zap2it