Sickle Cell Disease
It's an inherited disease marked by deformed red blood cells. These normally round and flexible cells take a sickle like shape.

Their irregular shape causes them to get stuck clogging vessels. This leads to pain, infection, and a shorter life.

The belief is that this incurable disease is found only in African Americans. But it can be found in any race. Which is why infants in all 50 states are tested at birth.