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Comedy writer Will Reiser was best friends with then-rising TV star Seth Rogen when he learned he had cancer in his 20s. Luckily, the writer survived and turned the experience into a screenplay. In the film, Joseph Gordon-Levitt (left) plays the twentysomething with cancer and Rogen plays the best friend. Oscar nominee Anna Kendrick plays the fumbling therapist who may capture his heart in this comedy drama.Toronto Film Festival