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Director: Jon Amiel — A biopic about Charles Darwin, the man behind the theory of evolution. Why: "Creation" breaks a longstanding rule at Toronto that a Canadian film must open the festival. Combine that with talented pairing of real-life husband and wife Paul Bettany and Oscar winner Jennifer Connelly and the controversial subject matter and the film becomes impossible to resist. Oscar chances: Connelly and Bettany are good bets for acting nominations, and if "Creation" can best the lukewarm response of 2004's "Kinsey," the film might be in store for some major acclaim. BBC Films