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Prentice Women's Hospital (222 E. Superior Street in Chicago)

This Bertrand Goldberg-designed building has been largely vacant since Northwestern's Women's Hospital relocated to a new structure in 2007. Ownership is expected to revert back to Northwestern University this year, when the last tenant moves out of the building. This concrete, clover leaf-shaped structure, which was built in 1975, would then likely be demolished for a new medical research facility. Although Goldberg's organic architectural designs -- such as this one -- were widely influential, none of his major Chicago works is protected by local landmark designation. Landmarks Illinois