The Twins scored the go-ahead run in the sixth inning on Brian Dozier's out-out single off reliever Troy Patton. Patton entered the game for starter Jake Arrieta, who left runners at first and second with no outs in the inning after a leadoff walk to Ryan Doumit and a single by Trevor Plouffe.
The Orioles tied the game 4-4 in the fifth inning when Adam Jones hit a run-scoring double over Twins center fielder Aaron Hicks, scoring Nick Markakis from first base to cut the Orioles’ deficit to one. Jones moved to third on the throw home, which skipped past catcher Ryan Doumit, and then scored on Chris Davis’ sacrifice fly to center to tie the game.
Davis’ game-tying RBI was his 12th this season through the first four games of the season.
Arrieta struggled in his third straight home opener start, allowing five runs on seven hits over five plus innings, stirking out five and walking two. While he looked strong at times, including during a 17-pitch first inning that included 14 strikes, he also couldn't get key outs when he needed them the most.
He allowed four runs in the top of the fourth. Arrieta was one strike away from getting out of the inning, opening Chris Parmelee with a 1-2 count before Parmelee slapped a full-count, two-out single up the middle that tied the game at one.
The Orioles squandered a huge opportunity against Twins starter Liam Hendriks in the bottom half of the inning.
After Adam Jones and Chris Davis opened the inning with back-to-back singles and Matt Wieters walked to load the bases, J.J. Hardy hit a ball to Escobar at short. Escobar threw to third for a force out, but Davis was called safe after third-base umpire Joe Cuzzi ruled that third baseman Trevor Plouffe never touched the bag.
That plated Jones to cut the lead to 4-2, but the Orioles then stranded the bases loaded with no outs.
The Orioles took a 1-0 lead in the first on Manny Machado’s single up the middle, scoring Nate McLouth from second.